2024 Week 12 NFL score predictions, game picks, odds: Model unveils exact scores from 10,000 simulations

Fans will be treated to several mouthwatering NFL matchups to bet on this week. Week 12 of the 2024 NFL schedule is jam-packed with star-studded showdowns, including Lions vs. Colts (+7.5, 50.5), 49ers vs. Packers (-2, 47.5), and Eagles vs. Rams (+3, 49). The Week 12 NFL schedule wraps up on Monday Night Football when Justin Herbert and the Los Angeles Chargers host Lamar Jackson and the Baltimore Ravens. The latest Week 12 NFL odds list the Ravens as three-point favorites on the road, one of the slimmest NFL betting lines of the week.

The Cowboys, meanwhile, enter their road tilt against the Commanders as 10.5-point underdogs according to the latest Week 12 NFL betting odds. Making NFL score predictions on all 13 games can help form not only NFL spread picks, but also NFL over-under picks, NFL parlays, and even NFL survivor strategy. Which Week 12 NFL games will be lopsided, and which ones will play out closer to their spreads? Before you make any Week 12 NFL picks, make sure you see what SportsLine’s advanced computer model has to say. 

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 12 of the 2024 NFL season on an incredible 20-8 betting hot streak on top-rated NFL picks this year. Longer term, it is on a 200-136 roll on top-rated NFL picks that dates back to the 2017 season and a 54-29 roll on top-rated NFL picks since Week 7 of 2022.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone following at sportsbooks and on betting apps has seen strong returns at their best sports betting app.

Now, the model has simulated every Week 12 game 10,000 times. You can only see the model’s Week 12 NFL exact score predictions at SportsLine.

Top Week 12 NFL picks

After diving into every game on the Week 12 NFL schedule, the model is backing the Denver Broncos (-6, 41) to beat the Las Vegas Raiders, 23-17, on the road. The Broncos have lost eight of their last nine games against the Raiders but they beat Las Vegas, 34-18, on Oct. 6 behind a strong showing from quarterback Bo Nix, who threw for 206 yards and two touchdowns. 

The Broncos are coming off a dominant 38-6 victory over the Falcons. Nix completed 84.8% of his passes for 307 yards and four touchdowns in the win over Atlanta. Nix has now thrown two or more touchdown passes in three of his past four games. Denver’s defense has also been exceptional this season, giving up 16.6 points per game, which ranks third in the NFL. SportsLine’s model projects Nix will throw for 202 yards and 1.61 touchdowns, while Denver’s defense racks up 3.74 sacks on average. See the model’s other Week 12 NFL score predictions at SportsLine. 

How to make Week 12 NFL score predictions

In addition, the model has locked in exact score predictions for this week’s biggest matchups including Cardinals vs. Seahawks, Eagles vs. Rams and Ravens vs. Chargers. It’s also calling for a Super Bowl contender to suffer a shocking defeat. Nailing these results is key to making profitable Week 12 NFL picks. You can only see them at SportsLine. 

Who wins each Week 12 NFL game, and which Super Bowl contender suffers a shocking defeat? Visit SportsLine now to get the model’s NFL Week 12 score predictions, all from the model on a 200-136 roll on top-rated NFL picks, and find out.