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NFL odds, Vegas lines, picks, spreads, game predictions: Model loves Ravens, Buccaneers in Week 2, 2024

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There are five NFL matchups between 1-0 teams on Sunday during the Week 2 NFL schedule, including Texans vs. Bears in primetime on Sunday Night Football. Bears rookie quarterback Caleb Williams was held under 100 passing yards in a win over Tennessee last week, but he is facing a Texans defense that allowed three passes of 50-plus yards to Indianapolis in their opener. Chicago is just 3-14 in road games since the start of the 2022 season, tied for the second-worst record in the NFL during that stretch. Houston is a 6.5-point favorite in the Week 2 NFL odds following its 29-27 win over the Colts, one of the largest NFL spreads of the week.

Other exciting matchups on Sunday include Cowboys (-6) vs. Saints, Lions (-7.5) vs. Buccaneers and Vikings (+4.5) vs. 49ers. Which games should you target with your Week 2 NFL predictions? All of the Week 2 NFL lines are listed below, and SportsLine’s advanced computer model has all the NFL betting advice and NFL predictions you need to make the best Week 2 NFL picks now.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on A-rated NFL picks since its inception. The model enters Week 2 of the 2024 NFL season on an incredible 184-130 run on top-rated NFL picks that dates back to the 2017 season. It is also on a 38-22 roll on A-rated NFL picks since Week 7 of the 2022 NFL season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, it has turned its attention to the latest Week 2 NFL odds and NFL betting lines on the spread, money line, and over-under, and locked in picks for every NFL matchup. Head here to see every pick.

Top Week 2 NFL predictions

We can tell you one of the model’s strongest Week 2 NFL picks is that the Ravens (-8.5, 41.5) cover at home versus the Raiders. Baltimore is coming off a narrow loss to Kansas City in the NFL Kickoff Game, but it will be able to dictate the pace of Sunday’s game. Running back Derrick Henry, who only had 13 carries against the Chiefs, is facing a Raiders defense that allowed 176 rushing yards to the Chargers last week and ranked outside the top 20 against the run last season.

Henry has only been held under 50 rushing yards in consecutive games three times since 2019, so this is the perfect opportunity for him to get back on track. Meanwhile, Ravens quarterback Lamar Jackson rushed for 122 yards in Week 1, and Baltimore went 3-0 against the spread following a loss last season. The Ravens have covered the spread in five of their last seven games as favorites, while the Raiders are 1-7 straight up in their last eight road games. See which other teams to pick here.

Another one of its Week 2 NFL predictions: the Buccaneers (+7.5, 51.5) cover on the road versus the Lions. After improving by six wins in Dan Campbell’s second season, the Lions were pegged for big things in 2023 and took a step towards the NFL’s upper echelon by tying a franchise record with 12 wins and making it to the 2024 NFC Championship Game. However, nobody saw Tampa Bay coming last season after Tom Brady retired.

Baker Mayfield went from stopgap option at quarterback to signing a $100 million extension this offseason and he dazzled in a Week 1 win over Washington. Mayfield went 24-of-30 for 289 yards and four touchdowns in a 37-20 win by the Bucs. With that passing game clicking on all cylinders early, the model is predicting that Tampa Bay covers the spread in 60% of simulations. See which other teams to pick here.

How to make Week 2 NFL picks

The model has also made the call on who wins and covers in every other game on the Week 2 NFL schedule and just revealed four coveted A-rated picks against the spread. You can only get every pick for every game at SportsLine.

So what NFL picks can you make with confidence, and which four A-rated NFL against-the-spread picks should you lock in now? Check out the latest NFL odds below, then visit SportsLine to see which teams win and cover the spread, all from a proven computer model that has returned well over $7,000, and find out.

Week 2 NFL betting odds, lines, spreads

Get Week 2 NFL picks at SportsLine

Sunday, Sept. 15

Raiders at Ravens (-8.5, 41.5)

Chargers at Panthers (+5, 39)

Saints at Cowboys (-6, 46.5)

Buccaneers at Lions (-7.5, 51.5)

Colts at Packers (+2.5, 40.5)

Browns at Jaguars (-3, 41.5)

49ers at Vikings (+4.5, 46.5)

Seahawks at Patriots (+3, 38.5)

Jets at Titans (+3.5, 41)

Giants at Commanders (-1.5, 43)

Rams at Cardinals (-1, 48)

Bengals at Chiefs (-6, 48)

Steelers at Broncos (+2.5, 36.5)

Bears at Texans (-6.5, 45.5)

Monday, Sept. 16

Falcons at Eagles (-6.5, 47)

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Author: CBS Sports Staff
September 14, 2024 | 4:45 pm

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